Endocrine Abstracts

A 54 year old woman was admitted by her GP to our Medical Admissions Unit earlier this year with a suspected diagnosis of malignancy due to her history of weight loss, lethargy and breathlessness. She was found to be hypercalcaemic with calcium of 3.35 mmol/l. Unfortunately, our acute physicians treated her with pamidronate before her hypercalcaemia was fully investigated which resulted in transient but symptomatic hypocalcaemia (with a nadir calcium of 1.72 mmol/l). A resti...

The four major hypertensive disorders in pregnancy are preeclampsia/eclampsia/HELLP syndrome, gestational hypertension, chronic hypertension and pre-eclampsia superimposed on chronic hypertension. The prevalence of hypertension in pregnancy has been reported to be around 6%. The commonest aetiology was found to be gestational hypertension which made up 40% of all cases. To our knowledge, secondary causes of hypertension in pregnancy has never been well described. We present a ...

Case report: A 29-year old Caucasian male was referred to our Endocrinology Outpatient Clinic following a recent admission after an episode of collapse when he was noted to have abnormal thyroid function tests: fT4 32.6 (7.5–21.1) pmol/l, TSH 6.41 (0.34–5.6) mU/l. These were repeated and again showed elevated fT4 26.9 pmol/l and normal TSH 2.29 mU/l. He reported some tremor of both hands but denied palpitations. He was clinically euthyroid but p...

Our patient presented at the age of 29 years with headaches and galactorrhoea and was found to have a prolactin level of more than 3000 mu/L. Her other pituitary function was normal. MRI pituitary showed 2×2 cm lesion with suprasellar extension and some distortion of the optic chiasm. She was started on Cabergoline 0.5 mg twice weekly for a presumed macroprolactinoma. Visual testing was normal. The repeat MRI four months after initiation of dopamine agonist therapy showed...

Background: We describe a 64-year-old lady with past medical history of Thalassaemia Trait and Hypertension, who was presented with Cushing’s syndrome.Clinical presentation: This patient was admitted with severe bi-basal pneumonia in February 2010 and treated successfully. But unfortunately her symptoms persisted with increasing facial swelling in end of May 2010, therefore, a staging CT was arranged and found incidental 6×5 cm left adrenal mas...